Kits and methods for autoantibody detection

摘要

An immunoassay method and test kit for detecting autoantibody in a patient sample, such as autoantibodies that interferes with the complexation of intrinsic factor with vitamin B12. A labeled receptor, i.e., intrinsic factor, is mixed with the sample and then with an anti-intrinsic factor antibody that binds competitively with the autoantibody to intrinsic factor bound to a solid phase is added and presence of autoantibody in the sample is determined.