PROCESS FOR PRODUCING STREPTOKINASE USING GENETICALLY MODIFIED ESCHERICHIA COLI
摘要
<p>An improved process for the production of streptokinase using a genetically engineered strain of Escherichia coli which overproduces streptokinase intracellularly and more particularly, the overall process disclosed herein, concerns with an improvement in the fermentative production of streptokinase using an optimized growth medium mainly comprised of simple salts and trace-elements; thus, in principal, the present process constitutes an improved and more economical means for the production of streptokinase which may be useful in thrombolytic therapy.</p>
申请公布号
WO2005066340(A1)
申请公布日期
2005.07.21
申请号
WO2003IB06243
申请日期
2003.12.23
申请人
COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH;VYAS, VINAY, VENKATRAO;RAJAMOHAN, GOVINDAN;RAMANDEEP, .;DIKSHIT, KANAK, LATA
发明人
VYAS, VINAY, VENKATRAO;RAJAMOHAN, GOVINDAN;RAMANDEEP, .;DIKSHIT, KANAK, LATA