发明名称 |
HIGHLY CONCENTRATED POURABLE AQUEOUS SOLUTIONS OF POTASSIUM IBUPROFEN, THEIR PREPARATION AND THEIR USES |
摘要 |
Concentrated pourable potassium ibuprofen liquid compositions and their preparation are described. They are comprised of (i) potassium ibuprofen, (ii) water; and (iii) methanol, ethanol, 1-propanol, 2-propanol, 1,1-dimethylethanol, or a mixture of any two or more of them. The amount of dissolved potassium ibuprofen in the composition is in the range of about 60 to about 90 wt%. These compositions are suitable for use in the preparation of pharmaceutical dosage form such as liquid-filled soft gelatin capsules, syrups, elixirs, suspensions; solid dosage forms such as tablets or caplets; and topically-applied products such as lotions, creams or ointments. |
申请公布号 |
WO2005065665(A2) |
申请公布日期 |
2005.07.21 |
申请号 |
WO2004US41584 |
申请日期 |
2004.12.13 |
申请人 |
ALBEMARLE CORPORATION;HU, PATRICK, C.;LAMBETH, GREGORY, H.;MALCOLM, ARCELIO, J. |
发明人 |
HU, PATRICK, C.;LAMBETH, GREGORY, H.;MALCOLM, ARCELIO, J. |
分类号 |
A61K9/48;A61K31/19;A61K31/192 |
主分类号 |
A61K9/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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