发明名称 |
Pharmaceutical formulations comprising paclitaxel, derivatives, and pharmaceutically acceptable salts thereof |
摘要 |
The invention concerns paclitaxel solubilizers and formulations thereof with a high propensity to dissolve paclitaxel. The formulations of the invention reduce or obviate the need for the disadvantageous excipient Cremophor(R) EL. The formulations of the invention are useful for administering paclitaxel, its derivatives, or pharmaceutically acceptable salts or such derivatives to patients in need thereof. The formulations of the invention are suitable for parenteral, oral, local, or transdermal administration to mammals including humans, particularly for intravenous delivery.
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申请公布号 |
US6919370(B2) |
申请公布日期 |
2005.07.19 |
申请号 |
US20030343780 |
申请日期 |
2003.02.03 |
申请人 |
TRANSFORM PHARMACEUTICALS, INC. |
发明人 |
CHEN HONGMING |
分类号 |
G01N33/15;A61K9/06;A61K9/08;A61K9/10;A61K9/107;A61K31/137;A61K31/28;A61K31/337;A61K31/4745;A61K45/00;A61K47/10;A61K47/14;A61K47/18;A61K47/26;A61K47/34;A61P35/00;A61P43/00;(IPC1-7):A61K31/335 |
主分类号 |
G01N33/15 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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