发明名称 |
Cyclohexylamine derivative as subtype selective NMDA receptor antagonists |
摘要 |
Described are compounds of Formula I and Formula II and their pharmaceutically acceptable salts. The compounds of Formulas I and II are antagonists of NMDA receptor channel complexes useful for treating cerebral vascular disorders such as, for example, cerebral ischemia, cardiac arrest, stroke, and Parkinson's disease.
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申请公布号 |
US6919377(B2) |
申请公布日期 |
2005.07.19 |
申请号 |
US20020258721 |
申请日期 |
2002.10.25 |
申请人 |
WARNER LAMBERT COMPANY LLC |
发明人 |
DEORAZIO RUSSELL JOSEPH;NIKAM SHAM SHRIDHAR;SCOTT IAN LESLIE;SHERER BRIAN ALAN;WISE LAWRENCE DAVID |
分类号 |
C07D213/74;A61K31/135;A61K31/136;A61K31/137;A61K31/138;A61K31/165;A61K31/27;A61K31/4402;A61K31/4406;A61K31/4409;A61K45/00;A61P3/00;A61P9/10;A61P13/02;A61P17/02;A61P25/00;A61P25/02;A61P25/04;A61P25/06;A61P25/08;A61P25/14;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P25/36;A61P27/02;A61P27/06;A61P27/16;A61P29/00;A61P43/00;C07C215/54;C07C215/56;C07C215/64;C07C217/16;C07C217/60;C07C217/62;C07C233/23;C07C235/14;C07C235/22;C07C271/24;C07C323/25;C07D213/38;(IPC1-7):C07D213/02;A61K31/44 |
主分类号 |
C07D213/74 |
代理机构 |
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代理人 |
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地址 |
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