VERFAHREN ZUR BEREITSTELLUNG VON WACHSTUMSFAKTOZUBEREITUNGEN (TGF-BETA UND IGF-1) MIT NIEDRIGER GEGENSEITIGER VERUNREINIGUNG AUS MILCHPRODUKTEN

摘要

The present invention relates to a process for extracting transforming growth factor beta (TGF- beta ) and insulin-like growth factor 1 (IGF-1) from a milk product, comprising the steps of: a) recovering a basic fraction from the milk product by means of cationic exchange chromatography; b) passing the fraction obtained in step a) over a hydroxyapatite column; c) eluting the hydroxyapatite column with appropriate eluents in such a way as to obtain two separate fractions, these fractions being: i) a fraction comprising IGF-1 in the substantial absence of TGF- beta ; ii) a fraction comprising TGF- beta in the substantial absence of IGF-1. This process can comprise a further step d) in which a lactoperoxidase fraction can be obtained. The invention further relates to the products obtained with this process.