发明名称 |
HYALURONIDASE ZUSAMMENSETZUNGEN ZUR BEHANDLUNG INTRAVITREALEN HEMORRHAGISCHEN BLUTES |
摘要 |
A thimerosal-free hyaluronidase is prepared wherein the preferred hyaluronidase is devoid of molecular weight fractions below 40,000 MW, between 60-70,000 MW and above 100,000 MW. Also a method for accelerating the clearance of hemorrhagic blood from the vitreous humor of the eye is carried out by contacting at least one hemorrhage-clearing enzyme (e.g., hyaluronidase, beta -glucuronidase, matrix metalloproteinase, chondroitinase, chondroitin sulfatase or protein kinase) with the vitreous humor in an amount which is effective to cause accelerated clearance of blood therefrom. |
申请公布号 |
AT298584(T) |
申请公布日期 |
2005.07.15 |
申请号 |
AT19960944203T |
申请日期 |
1996.11.20 |
申请人 |
ISTA PHARMACEUTICALS, INC. |
发明人 |
KARAGEOZIAN, HAMPAR L.;KARAGEOZIAN, VICKEN H.;KENNEY, MARIA C.;FLORES, JOSE L. G.;ARAGON, GABRIEL A. C.;NESBURN, ANTHONY B. |
分类号 |
A61K9/08;A61K31/00;A61K31/715;A61K38/00;A61K38/43;A61K38/46;A61K38/47;A61K38/48;A61K47/02;A61K47/26;A61P27/00;A61P27/02;(IPC1-7):A61K38/43 |
主分类号 |
A61K9/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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