发明名称 NOVEL SPIROINDOLINE OR SPIROISOQUINOLINE COMPOUNDS, METHODS OF USE AND COMPOSITIONS THEREOF
摘要 The invention provides compounds of Formula (I): and pharmaceutically acceptable salts, solvates and stereoisomers thereof, wherein A, B, E, G, W, X, Y, Z, o, and R1 are as disclosed herein ("Compound(s) of the Invention"), which are useful as cardio-protective and/or neuro-protective agents. The invention also provides pharmaceutical compositions comprising a Compound of the Invention and methods for treating, preventing and/or managing a vascular, cardiovascular or neurological disease or disorder, comprising administering to a patient in need thereof a Compound of the Invention.
申请公布号 WO2005063745(A2) 申请公布日期 2005.07.14
申请号 WO2004US43609 申请日期 2004.12.22
申请人 ARENA PHARMACEUTICALS, INC.;BOATMAN, DOUGLAS, P.;ADAMS, JOHN, W.;MOODY, JEANNE, V.;BABYCH, ERIC, D.;SCHRADER, THOMAS, O. 发明人 BOATMAN, DOUGLAS, P.;ADAMS, JOHN, W.;MOODY, JEANNE, V.;BABYCH, ERIC, D.;SCHRADER, THOMAS, O.
分类号 A61K31/40;A61K31/47;C07D471/10;G01N33/68;G01N33/94 主分类号 A61K31/40
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