发明名称 3-(4-BENZYLOXYPHENYL)PROPANOIC ACID DERIVATIVES
摘要 The present invention provides a novel compound represented by the formula ( I) wherein each symbol is as defined in the specification, a salt thereof and a prodrug thereof having a superior GPR40 receptor function modulating action, which can be used as an insulin secretagogue, an agent for the prophylaxis o r treatment of diabetes and the like. They unexpectedly show superior GPR40 receptor agonist activity, and also show superior properties as a pharmaceutical product, such as stability and the like. Thus, they can be sa fe and useful pharmaceutical agents for the prophylaxis or treatment of GPR40 receptor related diseases in mammals.
申请公布号 CA2551610(A1) 申请公布日期 2005.07.14
申请号 CA20042551610 申请日期 2004.12.24
申请人 TAKEDA PHARMACEUTICAL COMPANY LIMITED 发明人 NEGORO, NOBUYUKI;YASUMA, TSUNEO;KITAMURA, SHUJI
分类号 C07D309/12;C07C59/68;C07C59/72;C07C69/734;C07C205/34;C07C205/35;C07C217/20;C07C233/11;C07C233/18;C07C309/66;C07C317/18;C07C323/12;C07D207/08;C07D207/26;C07D207/27;C07D213/30;C07D277/24;C07D295/092;C07D295/18;C07D295/185;C07D295/205;C07D305/06;C07D333/32;C07D333/34;C07D335/02;C07F7/18;C07F9/40 主分类号 C07D309/12
代理机构 代理人
主权项
地址