发明名称 |
3-(4-BENZYLOXYPHENYL)PROPANOIC ACID DERIVATIVES |
摘要 |
The present invention provides a novel compound represented by the formula ( I) wherein each symbol is as defined in the specification, a salt thereof and a prodrug thereof having a superior GPR40 receptor function modulating action, which can be used as an insulin secretagogue, an agent for the prophylaxis o r treatment of diabetes and the like. They unexpectedly show superior GPR40 receptor agonist activity, and also show superior properties as a pharmaceutical product, such as stability and the like. Thus, they can be sa fe and useful pharmaceutical agents for the prophylaxis or treatment of GPR40 receptor related diseases in mammals.
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申请公布号 |
CA2551610(A1) |
申请公布日期 |
2005.07.14 |
申请号 |
CA20042551610 |
申请日期 |
2004.12.24 |
申请人 |
TAKEDA PHARMACEUTICAL COMPANY LIMITED |
发明人 |
NEGORO, NOBUYUKI;YASUMA, TSUNEO;KITAMURA, SHUJI |
分类号 |
C07D309/12;C07C59/68;C07C59/72;C07C69/734;C07C205/34;C07C205/35;C07C217/20;C07C233/11;C07C233/18;C07C309/66;C07C317/18;C07C323/12;C07D207/08;C07D207/26;C07D207/27;C07D213/30;C07D277/24;C07D295/092;C07D295/18;C07D295/185;C07D295/205;C07D305/06;C07D333/32;C07D333/34;C07D335/02;C07F7/18;C07F9/40 |
主分类号 |
C07D309/12 |
代理机构 |
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代理人 |
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地址 |
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