发明名称 |
Anti-inflamatory inhalation pharmaceutical composition |
摘要 |
The present invention is directed to the discovery of the anti-inflammatory properties of basic amino salts of acetylcysteine when administered directly to the lungs and/or the nose. This observed inflammation reduction in the lungs and/or the nasal cavity is confirmed by the diminution of at least one of the following inflammatory markers IL_6 and IL_8 and/or the increase in the lungs and/or the nasal cavity of the anti-inflammatory markers IL_10. The present invention also discloses pharmaceutical compositions for pulmonary and/or nasal administration of basic amino salts of acetylcysteine characterised that they have anti-inflammatory properties and may be useful to treat inflammatory lung and/or nasal conditions found in illnesses such as COPD, asthma, cystic fibrosis and the like.
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申请公布号 |
US2005154060(A1) |
申请公布日期 |
2005.07.14 |
申请号 |
US20040009017 |
申请日期 |
2004.12.13 |
申请人 |
GALEPHAR PHARMACEUTICAL RESEARCH, INC. |
发明人 |
DEBOECK ARTHUR;VANDERBIST FRANCIS;BAUDIER PHILLIPPE |
分类号 |
A61K31/198;(IPC1-7):A61K31/198 |
主分类号 |
A61K31/198 |
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