7H-IMIDAZO [1,2-alpha] PYRAZIN-8-ONE COMPOUNDS AS ION CHANNEL MODULATORS

摘要

N-substituted imidazopyrazinone compounds such as N-alkylated/aralkylated 7H-imidazo[1,2­a]pyrazin-8-one compounds and related analogs are disclosed. Pharmaceutical compositions and kits containing the N-substituted imidazopyrazinone compounds, as well as therapeutic uses thereof, including treatment of arrhythmia, are also disclosed.