发明名称 |
Vascular endothelial growth factor-x |
摘要 |
There is provided a novel vascular endothelial growth factor, herein designated VEGF-X, in addition to the nucleic acid molecule encoding it, a host cell transformed with said vector and compounds which inhibit or enhance angiogenesis. Also provided is the sequence of a CUB domain present in the sequence of VEGF-X which domain itself prevents angiogenesis and which is used to treat diseases associated with inappropriate vascularisation or angiogenesis.
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申请公布号 |
US2005153882(A1) |
申请公布日期 |
2005.07.14 |
申请号 |
US20040924025 |
申请日期 |
2004.08.23 |
申请人 |
JANSSEN PHARMACEUTICA N.V. |
发明人 |
GORDON ROBERT D.;SPRENGEL JORG J.;YON JEFFREY R.;DIJKMANS JOSIENA J.;GOSIEWSKA ANNA;DHANARAJ SRIDEVI N.;XU JEAN |
分类号 |
A61K38/00;C07K14/52;C12N5/02;(IPC1-7):A61K38/18;A61K48/00;C07K14/475;C07H21/04 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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