ANTIBODIES FOR ONCOGENIC STRAINS OF HPV AND METHODS OF THEIRUSE

摘要

The subject invention provides antibodies, including polyclonal and monoclon al antibodies, that bind to E6 proteins from at least three oncogenic strains o f HPV. In general, the antibodies bind to amino acids motifs that are conserve d between the E6 proteins of different HPV strains, particularly HPV strains 1 6 and 18. The subject antibodies may be used to detect HPV E6 protein in a sample, and, accordingly, the antibodies find use in a variety of diagnostic applications, including methods of diagnosing cancer. Kits for performing th e subject methods and containing the subject antibodies are also provided.