发明名称 Conjugated small molecules
摘要 Provided herein are linker compounds and conjugates that include the linker compounds. In one embodiment, the linker compounds comprise 2 or 3 residues of 6-aminohexanoic acid and optionally 7-10 residues of polyethyleneglycol (PEG). The linker compounds are useful in forming conjugates with one or more components useful in biopharmaceutical or bioanalytical applications. In particular, the biopharmaceutically useful compounds are kinase inhibitors. The conjugates described herein have utility in a variety of diagnostic, separation, and therapeutic applications.
申请公布号 US2005153371(A1) 申请公布日期 2005.07.14
申请号 US20050031638 申请日期 2005.01.07
申请人 AMBIT BIOSCIENCES CORPORATION 发明人 GROTZFELD ROBERT M.;MILANOV ZDRAVKO V.;PATEL HITESH K.;LAI ANDILIY G.;MEHTA SHAMAL A.;LOCKHART DAVID J.
分类号 C07D295/10;C07D295/24;C07D401/04;C07D403/12;C07D417/12;C07D417/14;C07D495/04;C07H19/04;G01N33/543;(IPC1-7):C12Q1/68;G01N33/53;A61K31/707;A61K31/418;A61K31/52;A61K31/506;A61K31/474;C07D498/02 主分类号 C07D295/10
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