发明名称 |
Peptides acting as both GLP-1 receptor agonists and glucagon receptor antagonists and their pharmacological methods of use |
摘要 |
The invention provides polypeptides that act both as an agonist of the GLP-1 receptor and an antagonist of the glucagon receptor. Such polypeptides are useful for treating individuals with type 2 diabetes or other metabolic disorders.
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申请公布号 |
US2005153890(A1) |
申请公布日期 |
2005.07.14 |
申请号 |
US20040999622 |
申请日期 |
2004.11.29 |
申请人 |
BAYER PHARMACEUTICALS CORPORATION |
发明人 |
PAN CLARK;WHELAN JAMES;CLAIRMONT KEVIN B. |
分类号 |
C12N15/09;A61K31/7088;A61K38/00;A61K38/22;A61K48/00;A61P3/00;A61P3/04;A61P3/08;A61P3/10;A61P43/00;C07K14/47;C07K14/575;C07K14/605;C07K14/745;C07K16/00;C07K16/18;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/00;C12P21/02;(IPC1-7):A61K38/17;C07H21/04;C07K16/28;C07K14/72 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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地址 |
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