发明名称 |
Synthetic and recombinant substrates for the detecion of the von willebrand factor-cleaving protease |
摘要 |
A method of detecting von Willebrand Factor-cleaving protease in a test sample is disclosed. In one embodiment, the method comprises the steps of (a) obtaining a test bodily fluid sample; (b) exposing the test sample to a monomeric von Willebrand Factor fragment, wherein the fragment comprises amino acids 842 and 843, wherein cleavage of the fragment will occur proportional to the amount of protease in the sample; and (c) comparing the cleavage products to a standard curve and determining the amount of von Willebrand Factor-cleaving protease in the test sample.
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申请公布号 |
US2005153383(A1) |
申请公布日期 |
2005.07.14 |
申请号 |
US20030333506 |
申请日期 |
2003.09.18 |
申请人 |
MONTGOMERY ROBERT R.;RAIFE THOMAS J.;HABERICHTER SANDRA L. |
发明人 |
MONTGOMERY ROBERT R.;RAIFE THOMAS J.;HABERICHTER SANDRA L. |
分类号 |
C12Q1/37;(IPC1-7):C12Q1/37 |
主分类号 |
C12Q1/37 |
代理机构 |
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主权项 |
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地址 |
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