发明名称 Synthetic and recombinant substrates for the detecion of the von willebrand factor-cleaving protease
摘要 A method of detecting von Willebrand Factor-cleaving protease in a test sample is disclosed. In one embodiment, the method comprises the steps of (a) obtaining a test bodily fluid sample; (b) exposing the test sample to a monomeric von Willebrand Factor fragment, wherein the fragment comprises amino acids 842 and 843, wherein cleavage of the fragment will occur proportional to the amount of protease in the sample; and (c) comparing the cleavage products to a standard curve and determining the amount of von Willebrand Factor-cleaving protease in the test sample.
申请公布号 US2005153383(A1) 申请公布日期 2005.07.14
申请号 US20030333506 申请日期 2003.09.18
申请人 MONTGOMERY ROBERT R.;RAIFE THOMAS J.;HABERICHTER SANDRA L. 发明人 MONTGOMERY ROBERT R.;RAIFE THOMAS J.;HABERICHTER SANDRA L.
分类号 C12Q1/37;(IPC1-7):C12Q1/37 主分类号 C12Q1/37
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