发明名称 Diaza-spiropiperidine derivatives
摘要 The present invention relates to compounds of formula wherein A-B is -CH<SUB>2</SUB>-CH<SUB>2</SUB>-, -CH<SUB>2</SUB>-O- or -O-CH<SUB>2</SUB>-; X is hydrogen or hydroxy; R<SUP>1 </SUP>is aryl, optionally substituted by one or two substituents selected from the group consisting of halogen, lower alkyl, cyano, CF<SUB>3</SUB>, -OCF<SUB>3</SUB>, lower alkoxy, -SO<SUB>2</SUB>-lower alkyl and heteroaryl; R<SUP>2 </SUP>is aryl, optionally substituted by one or two substituents selected from the group consisting of halogen, lower alkyl, CF<SUB>3</SUB>, and lower alkoxy; R<SUP>3 </SUP>is hydrogen or lower alkyl; n is 0, 1 or 2; or a pharmaceutically active salt thereof. The compounds of the invention may be used in the treatment of neurological and neuropsychiatric disorders.
申请公布号 US2005154001(A1) 申请公布日期 2005.07.14
申请号 US20050028281 申请日期 2005.01.03
申请人 CECCARELLI SIMONA M.;JOLIDON SYNESE;PINARD EMMANUEL;THOMAS ANDREW W. 发明人 CECCARELLI SIMONA M.;JOLIDON SYNESE;PINARD EMMANUEL;THOMAS ANDREW W.
分类号 C07D471/10;(IPC1-7):A61K31/474 主分类号 C07D471/10
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