PROCESS FOR PRODUCING SOLUTION CONTAINING UBIQUINONE-10

摘要

In accordance with the present invention, a process for producing a ubiquinone-10-containing solution is provided, which comprises the following steps: Ä1Ü adding a methanol solution to a culture obtained by culturing a microorganism having an ability to produce ubiquinone-10 in a medium, a processed product of the culture, or a partially purified product of ubiquinone-10, to a final concentration of 50 to 100 v/v% and then retaining the resulting mixture at a temperature of 0 DEG C or above to 30 DEG C or below; Ä2Ü separating and recovering an insoluble matter from the solution obtained at the step Ä1Ü; Ä3Ü adding a methanol solution of a concentration of 85 to 100 v/v% to the insoluble matter obtained in the step Ä2Ü and retaining the resulting mixture at a temperature of more than 30 DEG C and 80 DEG C or below; and Ä4Ü removing an insoluble matter from the solution obtained in the step Ä3Ü.