摘要 |
The present invention provides a compound represented by the general formula: <CHEM> Äwherein Ring A represents an optionally substituted 5- to 8-membered ring, Ring B represents a further optionally substituted 4- to 10-membered ring, Ring C represents a further optionally substituted benzene ring, X<1> represents carbon atom, X<2> represents a carbon atom, an oxygen atom, etc., W represents a nitrogen atom, etc., Y<11> represents a group represented by the formula CR<2>R<3'> (wherein R<2> represents a hydrogen atom, a cyano group, a nitro group, etc., and R<3'> represents a hydrogen atom, a cyano group, a nitro group, etc., respectively), Y<21> represents a group represented by the formula CR<4>R<5'> (wherein R<4> represents a hydrogen atom, a cyano group, a nitro group, etc., and R<5'> represents a hydrogen atom, a cyano group, a nitro group, etc., respectively), etc., and R<1> represents an electron-withdrawing group, respectively. The formula represents a single bond or a double bondÜ or a salt thereof, which is useful as an androgen receptor modulator.
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申请人 |
TAKEDA PHARMACEUTICAL COMPANY LIMITED |
发明人 |
SHIRAISHI, MITSURU;HARA, TAKAHITO;KUSAKA, MASAMI;KANZAKI, NAOYUKI;YAMAMOTO, SATOSHI;MIYAWAKI, TOSHIO |