发明名称 |
Method for immobilizing a biomolecule on a solid substrate at a high density by using the substrate having an activated carboxyl group on a surface thereof and microarray produced using the method |
摘要 |
Provided is a method for immobilizing a biomolecule on a solid substrate. The method includes coating the solid substrate with silane anhydride to introduce an anhydride functional group onto a surface of the solid substrate; obtaining a carboxyl group from the anhydride functional group by hydrolysis; reacting the carboxyl group with carbodiimide and succinimide to activate the carboxyl group; and contacting the biomolecule with the solid substrate having the activated carboxyl group on its surface to immobilize the biomolecule on the solid substrate. <IMAGE>
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申请公布号 |
EP1553415(A1) |
申请公布日期 |
2005.07.13 |
申请号 |
EP20050000285 |
申请日期 |
2005.01.07 |
申请人 |
SAMSUNG ELECTRONICS CO., LTD. |
发明人 |
HWANG, KYU-YOUN |
分类号 |
G01N33/547;C12N11/02;C12N15/09;G01N33/53;G01N33/543;G01N33/545;G01N33/552;G01N37/00;(IPC1-7):G01N33/543 |
主分类号 |
G01N33/547 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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