发明名称 |
ANTAGONIST OF MELANIN-CONCENTRATING HORMONE RECEPTOR COMPRISING BENZIMIDAZOLE DERIVATIVE AS ACTIVE INGREDIENT |
摘要 |
<p>This invention relates to a benzimidazole derivative of the general formula ÄIÜ <CHEM> Äwherein B<1>, B<2>, and B<3> represent hydrogen atom or lower alkyl; R<1> and R<2> are same or different and represent lower alkyl, etc.; R<3> and R<4> represent hydrogen atom, etc.; W represents a 3 to 8-membered aromatic or alphatic heterocycle, etc.; and Ar represents a substituted or unsubstituted aromatic heterocycle, etc.Ü This compound functions as an antagonist to melanin-concentrating hormone receptor and is useful as a drug for central diseases, circulatory diseases and metabolic diseases.</p> |
申请公布号 |
EP1553089(A1) |
申请公布日期 |
2005.07.13 |
申请号 |
EP20030771407 |
申请日期 |
2003.07.29 |
申请人 |
BANYU PHARMACEUTICAL CO., LTD. |
发明人 |
MORIYA, MINORU;KANATANI, AKIO,;IWAASA, HISASHI,;ISHIHARA, AKANE,;FUKAMI, TAKEHIRO, |
分类号 |
C07D235/30;A61K31/4184;A61K31/4196;A61K31/4245;A61K31/4439;A61K31/444;A61K31/454;A61K31/496;A61K31/497;A61K31/501;A61K31/506;A61K31/5377;A61K31/55;A61P1/00;A61P1/16;A61P3/00;A61P3/04;A61P3/06;A61P3/10;A61P25/00;C07D401/04;C07D401/12;C07D403/04;C07D403/12;C07D403/14;C07D407/12;C07D413/12;(IPC1-7):C07D235/30 |
主分类号 |
C07D235/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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