| 发明名称 |
OXA- AND THIADIAZOLES AND THEIR USE AS METALLOPROTEINASE INHIBITORS |
| 摘要 |
Compounds formula (IA) or (IB), wherein W represents HO(C-O)-, HONH(C-O)- or H(C-O)N(OH)-; X represents -O- or -S-; and R<SUB>1</SUB>, R<SUB>2</SUB>, and R<SUB>3 </SUB>are as defined in the description and claims, are inhibitors of matrix metal oproteinases, in particular MMP9 and/or MMP12. |
| 申请公布号 |
PL372268(A1) |
申请公布日期 |
2005.07.11 |
| 申请号 |
PL20030372268 |
申请日期 |
2003.02.20 |
| 申请人 |
VERNALIS OXFORD LTD.;LABORATOIRES SERONO SA |
发明人 |
AYSCOUGH ANDREW PAUL;DAVIES STEPHEN JOHN;PAIN GILLES;GILLON JEAN-YVES |
| 分类号 |
A61K31/4245;A61P1/00;A61P1/02;A61P1/04;A61P1/16;A61P9/10;A61P11/00;A61P11/06;A61P11/08;A61P13/12;A61P17/00;A61P17/02;A61P17/06;A61P19/02;A61P19/08;A61P25/00;A61P25/02;A61P27/02;A61P29/00;A61P31/04;A61P35/00;A61P35/04;A61P37/02;A61P37/06;A61P43/00;C07D271/06;C07D285/08;C07D413/04;C07D413/06 |
主分类号 |
A61K31/4245 |
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