发明名称 Macromolecular drug complexes having improved stability and therapeutic use of the same
摘要 Macromolecular drug complexes containing a protein therapeutic, like human growth hormone, and an excess stoichiometric molar amount of a polymer, like heparin, and compositions containing the same, are disclosed. Compositions containing the macromolecular drug complexes are administered, including via pulmonary delivery, to individuals suffering from a disease or condition, and the complexes release the protein therapeutic, in vivo, to treat the disease or condition.
申请公布号 US2005147581(A1) 申请公布日期 2005.07.07
申请号 US20040987503 申请日期 2004.11.12
申请人 THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 发明人 ZAMIRI CAMELLIA;GROVES MICHAEL J.
分类号 A61K9/00;A61K9/14;A61K9/16;A61K9/19;A61K31/727;A61K31/785;A61K38/09;A61K38/11;A61K38/17;A61K38/18;A61K38/19;A61K38/20;A61K38/21;A61K38/23;A61K38/24;A61K38/25;A61K38/26;A61K38/27;A61K38/28;A61K38/30;A61K38/33;A61K38/36;A61K38/37;A61K38/38;A61K38/47;A61K38/48;A61K47/48;(IPC1-7):A61K38/28 主分类号 A61K9/00
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