| 发明名称 |
PROCESS FOR MAKING CAMPTOTHECIN DERIVATIVES |
| 摘要 |
<p>A process for synthesizing highly lipophilic derivatives of camptothecin. The process includes reacting dissolved, underivatized camptothecin with a silylated heterocyclic compound in a modified Minisci-type alkylation reaction to produce 7-substituted derivatives of camptothecin.</p> |
| 申请公布号 |
WO2005061517(A1) |
申请公布日期 |
2005.07.07 |
| 申请号 |
WO2004US36192 |
申请日期 |
2004.11.01 |
| 申请人 |
BIONUMERIK PHARMACEUTICALS, INC. |
发明人 |
WU, YE;NARKUNAN, KESAVARAM;WANG, JIANYAN;KOCHAT, HARRY |
| 分类号 |
C07D491/147;C07D491/22;(IPC1-7):C07D491/22 |
主分类号 |
C07D491/147 |
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