发明名称 |
LFA-1 antagonist compounds |
摘要 |
The invention relates to novel compounds having formula (I) wherein Cy, X, Y, L and R<SUB>1-6 </SUB>are as defined herein. The compounds bind CD11/CD18 adhesion receptors such as Lymphocyte Function-associated Antigen-1 (LFA-1) and are therefore useful for treating disorders mediated by LFA-1 such as inflammation and autoimmune diseases.
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申请公布号 |
US2005148588(A1) |
申请公布日期 |
2005.07.07 |
申请号 |
US20050040639 |
申请日期 |
2005.01.21 |
申请人 |
GENENTECH, INC. |
发明人 |
BURDICK DANIEL J.;STANLEY MARK S.;OARE DAVID;REYNOLDS MARK E.;GADEK THOMAS R.;MARSTERS JAMES C.JR. |
分类号 |
C07D277/06;A61K31/197;A61K31/198;A61K31/341;A61K31/351;A61K31/385;A61K31/40;A61K31/4015;A61K31/4025;A61K31/403;A61K31/426;A61K31/427;A61K31/44;A61K31/445;A61K31/4458;A61K31/4462;A61K31/4465;A61K31/4525;A61P1/04;A61P11/06;A61P17/06;A61P19/02;A61P29/00;A61P37/06;C07C233/83;C07D207/16;C07D211/60;C07D211/62;C07D307/54;C07D405/12;C07D407/12;C07D409/12;C07D417/12;(IPC1-7):A61K31/537;A61K31/495;A61K31/421;A61K31/195;A61K31/381 |
主分类号 |
C07D277/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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