摘要 |
The invention provides a combination of compositions for treating, preventing, reversing or inhibiting pain, wherein at least one composition comprises a nitration inhibitor. Further provided is a method wherein the nitration inhibitor is selected from the group consisting of a SO generating system inhibitor, SO scavenger, NOS inhibitor, NO generating system inhibitor, NO scavenger, peroxynitrite generating system inhibitor, peroxynitrite scavenger, and any combination thereof. Preferably, the nitration inhibitor is combined with a pain inhibitor. The pain inhibitor is still more preferably an opioid. |