发明名称 |
A NOVEL CATIONIC LIPOPOLYMER AS A BIOCOMPATIBLE GENE DELIVERY AGENT |
摘要 |
A biodegradable cationic lipopolymer comprising a polyethylenimine (PEI), a lipid, and a biocompatible hydrophilic polymer, wherein 1) the lipid and the biocompatible hydrophilic polymer are directly linked to the PEI backbone or 2) the lipid is linked to the PEI backbone through the biocompatible hydrophilic polymer. The cationic lipopolymers of the present invention can be used for delivery of a nucleic acid or any anionic bioactive agent to variou s organs and tissues after local or systemic administration.
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申请公布号 |
CA2539169(A1) |
申请公布日期 |
2005.07.07 |
申请号 |
CA20032539169 |
申请日期 |
2003.12.10 |
申请人 |
EXPRESSION GENETICS, INC. |
发明人 |
HAN, SANG-OH;MAHATO, RAM I.;ANWER, KHURSHEED;FURGESON, DARIN Y. |
分类号 |
A61K9/127;A61K47/48;A61K48/00;C08G73/02 |
主分类号 |
A61K9/127 |
代理机构 |
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