发明名称 |
HUMANIZED ANTI-CCR2 ANTIBODIES AND METHODS OF USE |
摘要 |
The present invention relates to a humanized antibody or functional fragment thereof which binds to a mammalian (e.g., human) CC-chemokine receptor 2 (CCR2) or a portion of the receptor and blocks binding of a ligand to the receptor. The invention further relates to a method of inhibiting the interaction of a cell bearing mammalian CCR2 with a ligand thereof, and to use of the antibodies and fragments in therapeutic, prophylactic and diagnostic methods. |
申请公布号 |
WO2005060368(A2) |
申请公布日期 |
2005.07.07 |
申请号 |
WO2003US39599 |
申请日期 |
2003.12.10 |
申请人 |
MILLENNIUM PHARMACEUTICALS, INC.;O'KEEFE, THERESA;PONATH, PAUL |
发明人 |
O'KEEFE, THERESA;PONATH, PAUL |
分类号 |
A61K39/395;C07K16/28 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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