发明名称 |
CONTRAST MEDIUM FOR X-RAY EXAMINATION |
摘要 |
<P>PROBLEM TO BE SOLVED: To provide an X-ray contrast medium which is highly safe and has a proper half-life, and to provide a method for producing the same. <P>SOLUTION: This contrast medium for X-ray examination is characterized by containing liposomes containing a water-soluble and nonionic iodine compound and having a blood retention time of 0.25 to 4 hours as a half-life. The above-mentioned liposome is preferably a single membrane liposome. The central particle diameter of the liposome is preferably 50 to 500 nm. The liposome is especially preferably a PEG-reacted liposome containing the PEG having oxyethylene units of 10 to 3,500 in an amount of 0.1 to 30 mass % based on the lipid constituting the liposome. <P>COPYRIGHT: (C)2005,JPO&NCIPI |
申请公布号 |
JP2005179214(A) |
申请公布日期 |
2005.07.07 |
申请号 |
JP20030419848 |
申请日期 |
2003.12.17 |
申请人 |
KONICA MINOLTA MEDICAL & GRAPHIC INC |
发明人 |
NAGAIKE CHIAKI;NAKAJIMA AKIHISA;UEDA EIICHI |
分类号 |
A61K9/127;A61K47/34;A61K49/04 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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