发明名称 |
Automated immunoassay cassette, apparatus and method |
摘要 |
An immunoassay cassette, apparatus, and method for detecting an analyte in a liquid body-fluid sample are disclosed. The cassette has a body and a support mounted on the body, for movement relative to the body to first and second transfer positions. Sample supplied to a sample well in the cassette body is transferred to a reagent reservoir on the cassette body, by moving the support to its first transfer position. Here the sample reacts with a first reagent composition in the reservoir effective to form a modified sample. The modified sample is then transferred to a reagent strip on the support by moving the support to its second transfer position. The reagent strip has a transfer zone at which sample material is transferred to the strip, a second reagent composition effective to react with the modified sample to form a detectable analyte-dependent product, and a detection zone located downstream at which the detectable product can be observed. By controlling movement of the support to its first and second positions, the cassette can effectively handle a variety of samples having different flow rates.
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申请公布号 |
US2005147532(A1) |
申请公布日期 |
2005.07.07 |
申请号 |
US20040016016 |
申请日期 |
2004.12.17 |
申请人 |
BELLET NEAL F.;SHINDELMAN JEFFREY;WORTHY THOMAS E.;HALEY KIMBERLY;LEE RICHARD K.;KYUNG JANE E.;QIAN SUYUE |
发明人 |
BELLET NEAL F.;SHINDELMAN JEFFREY;WORTHY THOMAS E.;HALEY KIMBERLY;LEE RICHARD K.;KYUNG JANE E.;QIAN SUYUE |
分类号 |
B01L3/00;B01L9/00;G01N33/543;(IPC1-7):G01N21/00 |
主分类号 |
B01L3/00 |
代理机构 |
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代理人 |
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地址 |
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