发明名称 |
COMPOSITION AND METHODS FOR MODULATING CNS ACTIVITY |
摘要 |
The present invention concerns the methods and compositions for treating depression and other behavioral and/or emotional disorders of the central nervous system by administering an agonist of hedgehog signaling. Other disorders amenable to treatment by the subject method include attention deficit hyperactive disorders, non-Alzheimer dementia, and various symptoms of memory loss. The present invention also concerns the methods and compositions for enhancing memory and/or cognitive functions, both in a patient suffering from ailment affecting these functions, and in a subject with no diagnosed deficit in memory or cognitive function. The methods and compositions of the present invention stimulate neurogenesis and differentiation, and enhance synaptic transmission of neurons. |
申请公布号 |
WO2005061002(A2) |
申请公布日期 |
2005.07.07 |
申请号 |
WO2004US42271 |
申请日期 |
2004.12.15 |
申请人 |
CURIS, INC.;RUBIN, LEE, L. |
发明人 |
RUBIN, LEE, L. |
分类号 |
A61K38/17;A61K48/00;C12Q1/68 |
主分类号 |
A61K38/17 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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