摘要 |
The invention relates to a rapid DNA selection method involving the manipulation of certain DNA properties and hybridisation conditions. Unlike some existing methods, the invention does not require the use of enzymes or complex probe immobilisation systems and, as a result, is a simple, quick, reliable, low-cost and efficient method of recovering positive clones. The inventive method provides a valuable tool for the selection and/or purification of DNA fragments from a gene or expression bank.
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