发明名称 |
Human mesencephalon cell lines and methods of use therefor |
摘要 |
Conditionally-immortalized human mesencephalon cell lines are provided. Such cell lines, which may be clonal, may be used to generate neurons, including dopaminergic neurons. The cell lines and/or differentiated cells may be used for the development of therapeutic agents to prevent and treat a variety of neurological diseases such as Parkinson's disease. The cell lines and/or differentiated cells may also be used in assays and for the general study of mesencephalon cell development and differentiation.
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申请公布号 |
US6913925(B1) |
申请公布日期 |
2005.07.05 |
申请号 |
US19980134771 |
申请日期 |
1998.08.12 |
申请人 |
SIGNAL PHARMACEUTICALS LLC |
发明人 |
SAH DINAH W. Y.;RAYMON HEATHER K. |
分类号 |
G01N33/50;A61K35/12;A61K35/30;A61K48/00;A61P25/16;C12N5/0797;C12N5/10;C12N15/09;C12Q1/04;C12Q1/68;C12R1/91;G01N33/15;(IPC1-7):C12N5/08;C12N5/00;C12N15/00;C12N15/63;C12P21/06 |
主分类号 |
G01N33/50 |
代理机构 |
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地址 |
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