发明名称 Macrocyclic NS-3 serine protease inhibitors of hepatitis C virus comprising alkyl and aryl alanine P2 moieties
摘要 The present invention discloses novel macrocyclic compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such macrocycles as well as methods of using them to treat disorders associated with the HCV protease.
申请公布号 US6914122(B2) 申请公布日期 2005.07.05
申请号 US20010836636 申请日期 2001.04.17
申请人 SCHERING CORPORATION 发明人 VENKATRAMAN SRIKANTH;CHEN KEVIN X.;ARASAPPAN ASHOK;NJOROGE F. GEORGE;GIRIJAVALLABHAN VIYYOOR MOOPIL;GANGULY ASHIT K.;CHAN TIN-YAU;MC KITTRICK BRIAN ALEXANDER;YAO NANHUA HUGH;PRONGAY ANDREW JOSEPH;MADISON VINCENT STEWART
分类号 A61K45/00;A61K31/7052;A61K38/00;A61K38/21;A61P31/12;A61P31/14;A61P43/00;C07D273/00;C07K5/02;C07K7/02;C07K7/64;(IPC1-7):C07K7/50 主分类号 A61K45/00
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