<p>The present invention relates to methods for inhibiting cathepsin K activity in a mammal in need thereof comprising administering a nitric oxide donor compound having cathepsin K inhibition activity. The present invention also relates to methods for inhibiting bone resorption in a mammal comprising administering to a mammal in need thereof a therapeutically effective amount of such a nitric oxide donor. The present invention also relates to compositions comprising such a nitric oxide donor.</p>
申请公布号
DE60020365(D1)
申请公布日期
2005.06.30
申请号
DE2000620365
申请日期
2000.02.24
申请人
THOMAS SWAN AND CO., LTD.
发明人
POLIAKOFF, MARTYN;GRAY, WILLIAM KEITH;SWAN, THOMAS MACKLYN;ROSS, STEPHEN KEITH;WIELAND, STEFAN;ROEDER, STEFAN