发明名称 |
ESTIMATING GENE NETWORKS USING INFERENTIAL METHODS AND BIOLOGICAL CONSTRAINTS |
摘要 |
The accurate estimation of gene networks from gene expression measurements i s a major challenge in the field of Bioinformatics. We present a general approach to reduce the search space to a biologically meaningful subspace an d to find optimal solutions within the subspace in linear time by using inferential models constrained by biologically relevant information. We show ed the effectiveness of this approach in application to yeast and Bacillus subtilis data. Also, we provide systems and storage media adapted to provide and store data and results of gene network relationships.
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申请公布号 |
CA2549010(A1) |
申请公布日期 |
2005.06.30 |
申请号 |
CA20042549010 |
申请日期 |
2004.12.13 |
申请人 |
GNI USA;GNI LTD. |
发明人 |
OTT, SASCHA;MIYANO, SATORU |
分类号 |
G01N33/48;G06F;G06F19/12;G06F19/20;G06F19/24 |
主分类号 |
G01N33/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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