| 摘要 |
PROBLEM TO BE SOLVED: To provide a production method of fine particle which is capable of preventing the incorporation of foreign matters, reliably performing washing and sterilization, responding to CIP(cleaning in place)/SIP(sterilization in place), steadily performing a stable operation without danger of misoperation and performing high precision dispersion, crushing, emulsification and liposome formation, and to provide an apparatus therefor. SOLUTION: Materials to be pulverized are introduced between at least two sheets of elastomers having a hardness higher than the hardness of the material to be pulverized, subsequently, at least one sheet of elastomers is vibrated and, thereby, the material to be pulverized is ground between the elastomers. COPYRIGHT: (C)2005,JPO&NCIPI
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