Device for controlled reservoir opening with reinforced reservoir caps

摘要

Device are provided for the controlled release or exposure of molecules or secondary devices comprising a substrate; a plurality of reservoirs located in the substrate; reservoir contents comprising molecules, a secondary device, or both, isolated inside the reservoirs; reservoir caps positioned on the reservoirs over the reservoir contents, wherein the reservoir caps (which can comprise a metal film) are mechanically reinforced with a second material deposited and patterned on the surface of the metal film inside the reservoir or on the surface of the metal film outside the reservoir or on both of said surfaces; and control circuitry and a power source for disintegrating the reservoir caps to initiate exposure or release of the reservoir contents in selected reservoirs.