摘要 |
PROBLEM TO BE SOLVED: To provide a novel method, by which a single patient sample is analyzed, and the levels of thyrotropic hormones and anti-thyroxine are measured simultaneously. SOLUTION: The single patient sample is subjected to an incubation process, along with a particulate mixture in a first suspension. The particulate mixture is composed of particles covered by the thyrotropic hormone and a particle covered by the anti-thyroxine, and the particles can be distinguished from each other through a flow cytometry process. The particles are recovered from the first suspension, and the recovered particles are subjected to the incubation process along with a mixture of labeled binding members in a second suspension. The mixture of the labeled binding members is composed of labeled anti-thyrotropic hormone and a labeled analog, toward which the anti-thyroxine has immunological affinity and in which the immunological affinity is less than that of the anti-thyroxine toward thyroxine. COPYRIGHT: (C)2005,JPO&NCIPI
|