发明名称 |
DETECTION OF CELL MEMBRANE-ASSOCIATED PROTEINS USING MEMBRANE FRAGMENTS DISPLAYED ON ENCODED MICROPARTICLE ARRAYS |
摘要 |
Disclosed are methods relating to cell membrane fragments associated with microbeads, so that the characteristics of the cells the fragments originated from can be determined. The fragments can be oriented with what was the outer surface of the cell membrane facing outwardly, so that the antigens associated with the membrane can be contact with ligands (including antibodies) to antigens in the membranes which would be accessible to antibodies in vivo. The system is useful, inter alia, for detection of panel reactive antibodies in donor serum, as well as detection of other cell membrane antigens; or quantitation of particular cell membrane antigens. |
申请公布号 |
WO2005006960(A3) |
申请公布日期 |
2005.06.30 |
申请号 |
WO2004US22782 |
申请日期 |
2004.07.15 |
申请人 |
BIOARRAY SOLUTIONS LTD.;SEUL, MICHAEL;YANG, JIACHENG;TAN, ENQING |
发明人 |
SEUL, MICHAEL;YANG, JIACHENG;TAN, ENQING |
分类号 |
A61B;C12M1/34;C12Q1/68;G01N33/53;G01N33/543;G01N33/564;G01N33/567;G01N33/569;G01N33/68 |
主分类号 |
A61B |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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