MOLECULAR STAMP FOR PRINTING BIOMOLECULES ONTO A SUBSTRATE

摘要

The invention pertains to a molecular stamp for printing biomolecules onto a substrate comprising a hydrophylic polymeric gel and a patterned surface, characterized in that the gel has at least 20 % crosslink density. Preferably, the stamp comprises a gel which is obtainable by polymerizing at least one of a water soluble ethylenically unsaturated and/or epoxidated monomer containing at least one functional group selected from a hydroxyl, alkoxyl, amine, alkyl substituted amine, carboxylic acid, carboxylic ester, carboxylic anhydride, carboxamide, isocyanate, carbamate, urethane, and urea group, in the presence of a polymerization initiator and optionally a chain transfer agent, and crosslinking the polymer with a crosslinker having at least two ethylenically unsaturated groups and/or epoxy groups.