N-(4-CARBAMIMIDOYL-BENZYL) -2-ALKOXY-2-HETEROCYCLYL ACETAMIDES AS INHIBITORS OF THE FORMATION OF COAGULATION FACTORS XA, IXA AND THROMBIN INDUCED BY FACTOR VIIA
摘要
<p>The invention is concerned with novel heterocyclyl substituted mandelic acid derivatives of formula (I) wherein R<1> to R<6> and A are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds inhibit the formation of coagulation factors Xa, IXa and thrombin induced by factor VIIa and tissue factor and can be used as medicaments.</p>
申请公布号
WO2005058868(A1)
申请公布日期
2005.06.30
申请号
WO2004EP14185
申请日期
2004.12.13
申请人
F. HOFFMANN-LA ROCHE AG;GOBBI, LUCA, CLAUDIO;GROEBKE ZBINDEN, KATRIN;MOHR, PETER;OBST, ULRIKE