| 摘要 |
PROBLEM TO BE SOLVED: To provide a new monomethyl malonate derivative useful for obtaining an indanonecarboxylic acid ester having a halogen atom on the indanone ring. SOLUTION: The monomethyl malonate derivative is represented by formula (I) (wherein, X denotes a halogen atom; and Me denotes a methyl group). The compound can be produced by carrying out (A) a step of reacting a benzyl halide derivative represented by formula (II) (wherein, X and Y are each the same or different and denote each a halogen atom) with dimethyl malonate in the presence of a base and providing a dimethyl malonate derivative represented by formula (III) äwherein, X is the same as described in formula (I); and Me denotes a methyl group} and (B) a step of hydrolyzing the resultant dimethyl malonate derivative represented by formula (III). COPYRIGHT: (C)2005,JPO&NCIPI
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