发明名称 ADVANCED GLYCATION END-PRODUCT INTERMEDIATE AND INHIBITION OF POST-AMADORI TRANSFER
摘要 PROBLEM TO BE SOLVED: To provide a pharmaceutical for treating one or more diseases selected from the group consisting of diabetic nephropathy, proteinuria, impairment of glomerular clearance, and diabetic retinopathy and inhibiting post-Amadori advanced glycation end-product (AGE) formation. SOLUTION: The pharmaceutical contains pyridoxamine and is used for treating the diseases, wherein the diabetic nephropathy is included in the diseases, the proteinuria is included in the diseases, the impairment of the glomerular clearance is included in the diseases, and the diabetic retinopathy is included in the diseases. Further, the pharmaceutical inhibits the post-Amadori AGE formation. COPYRIGHT: (C)2005,JPO&NCIPI
申请公布号 JP2005170935(A) 申请公布日期 2005.06.30
申请号 JP20040334202 申请日期 2004.11.18
申请人 UNIV OF KANSAS MEDICAL CENTER 发明人 HUDSON BILLY G;TODD PARVIN;KHALIFAH RAJA GABRIEL;BOOTH AARON ASHLEY
分类号 C07H5/04;A61K31/00;A61K31/04;A61K31/155;A61K31/435;A61K31/44;A61K31/4409;A61K31/4412;A61K31/4415;A61K31/506;A61K31/51;A61K31/675;A61K38/05;A61K38/06;A61K38/07;A61P3/00;A61P3/10;A61P9/10;A61P13/00;A61P13/12;A61P27/06;A61P43/00;C07D213/66;C07D417/06;C07K1/02;C07K5/06;C07K5/087;C07K14/00;G01N33/68;(IPC1-7):A61K31/440 主分类号 C07H5/04
代理机构 代理人
主权项
地址
您可能感兴趣的专利