发明名称 |
Robust genotyping method using DNA chip having discriminating probe and amplicon probe immobilized thereon and DNA chip used therein |
摘要 |
Provided is a genotyping method. The genotyping method includes using a DNA chip on which just an optimal probe set is immobilized, the optimal probe sets composed of a discriminating probe which perfectly matches a mutant type gene or a wild type gene for each of at least one identified mutation site in each of at least one amplicon contained in a sample and an amplicon probe having a sequence which perfectly matches a region excluding a nucleotide sequence at a mutation site in each amplicon and is absent from the other amplicons, in order to identify which one of a wild type gene and a mutant type gene is present in each mutation site. In this genotyping method, the number of probes used can be reduced and reliability of genotyping results can be increased.
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申请公布号 |
US2005142599(A1) |
申请公布日期 |
2005.06.30 |
申请号 |
US20040019011 |
申请日期 |
2004.12.21 |
申请人 |
SHIM HYEONG-SOP;KIM JONG-MIN;OH JI-YOUNG |
发明人 |
SHIM HYEONG-SOP;KIM JONG-MIN;OH JI-YOUNG |
分类号 |
C12Q1/68;G01N33/48;G01N33/50;G06F19/00;(IPC1-7):C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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