METHODS, PROGRAMPRODUCTS, AND SYSTEMS FOR SINGLE AND MULTI-AGENT DOSING AND OTHER RELATED METHODS

摘要

Methods, program product (442), and systems (400) for single and multi-agent dosing are provided. An embodiment of a method for revising a cycle dose of at least one agent for a patient receiving a single or multi-agent therapy includes accepting as a first input the patient's cycle dose(s) of the at least one agent (101), accepting as a second input determination of the relevancy of at least one surrogate marker indicating a pharmacologic response of the patient (102) and determining a revised dose of the at least one agent (105). Embodiments of systems (400) and program products (442) are also provided for use in calculating revised dose of at least one agent.