发明名称 HUMAN IPLA2T
摘要 A novel function phospholipase A2, referred to herein as calcium­independent phospholipase A2< (IPLA2?) having SEQ ID NO: 1 and SEQ ID NO: 2, and nucleic acid sequences (SEQ ID NO: 3 and SEQ ID NO: 4) encoding and expressing iPLA2?. This novel enzyme has been isolated and characterized and is involved in the catalysis and hydrolysis of lipids cycling in a living cell biosystem. In an embodiment, the compromises to an isolated nucleic acid molecule comprising a set of iPLA2? polynucleotides. In an aspect of this embodiment, the iPLA2? polynucleotides encode and express an iPLA2? polypeptide. In one aspect, an isolated and characterized gene comprises a polynucleotide having a sequence shown in SEQ ID NO: 3 and SEQ ID NO: 4.
申请公布号 WO2005059099(A2) 申请公布日期 2005.06.30
申请号 WO2004US41619 申请日期 2004.12.13
申请人 WASHINGTON UNIVERSITY IN ST.LOUIS;GROSS, RICHARD;JENKINS, CHRISTOPHER, M. 发明人 GROSS, RICHARD;JENKINS, CHRISTOPHER, M.
分类号 A61K38/00;C07H21/04;C12N;C12N9/20 主分类号 A61K38/00
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