| 摘要 |
Polyoxometalate compounds which exhibit anti-retroviral activity are disclosed. Compounds with anti-retroviral activity include those having the following general molecular formulas: <?in-line-formulae description="In-line Formulae" end="lead"?>M<SUB>7</SUB>PW<SUB>11</SUB>O<SUB>39 </SUB><?in-line-formulae description="In-line Formulae" end="tail"?> <?in-line-formulae description="In-line Formulae" end="lead"?>M<SUB>8</SUB>SiW<SUB>11</SUB>O<SUB>39 </SUB><?in-line-formulae description="In-line Formulae" end="tail"?> <?in-line-formulae description="In-line Formulae" end="lead"?>M<SUB>9</SUB>HSiW<SUB>9</SUB>O<SUB>34 </SUB><?in-line-formulae description="In-line Formulae" end="tail"?> <?in-line-formulae description="In-line Formulae" end="lead"?>M<SUB>8</SUB>HPW<SUB>9</SUB>O<SUB>34 </SUB><?in-line-formulae description="In-line Formulae" end="tail"?> <?in-line-formulae description="In-line Formulae" end="lead"?>M<SUB>10</SUB>(TM)<SUB>4</SUB>(PW<SUB>9</SUB>O<SUB>34</SUB>)<SUB>2 </SUB><?in-line-formulae description="In-line Formulae" end="tail"?> <?in-line-formulae description="In-line Formulae" end="lead"?>M<SUB>16</SUB>(TM)<SUB>4</SUB>(P<SUB>2</SUB>W<SUB>15</SUB>O<SUB>56</SUB>)<SUB>2 </SUB><?in-line-formulae description="In-line Formulae" end="tail"?> <?in-line-formulae description="In-line Formulae" end="lead"?>M<SUB>14</SUB>[NaP<SUB>5</SUB>W<SUB>30</SUB>O<SUB>110</SUB>]<?in-line-formulae description="In-line Formulae" end="tail"?> <?in-line-formulae description="In-line Formulae" end="lead"?>M<SUB>12</SUB>(TM)<SUB>3</SUB>(PW<SUB>9</SUB>O<SUB>34</SUB>)<SUB>2 </SUB><?in-line-formulae description="In-line Formulae" end="tail"?> <?in-line-formulae description="In-line Formulae" end="lead"?>M<SUB>6</SUB>P<SUB>2</SUB>W<SUB>18</SUB>O<SUB>62 </SUB><?in-line-formulae description="In-line Formulae" end="tail"?> wherein M is an alkali metal, NH<SUB>4</SUB><SUP>+</SUP> or other common monocation or soluble dication, or any combination of the above provided adequate water solubility is exhibited, or histidinium ion, argininium ion, or lysinium ion or any dication of a dipeptide or oligopeptide with 2 protonated basic amino acid residues, or any combination of these monocations or dications with each other or with any common inorganic cation, and TM is a divalent transition metal ion, such as Mn, Fe, Co, Ni, Cu and Zn.
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