发明名称 |
TAXANE DERIVATIVES AND DRUGS CONTAINING THE SAME |
摘要 |
- 154 - This invention relates to a taxane derivative represented by the following formula (1): <IMG> wherein at least one of X and Y represents a group -CO-A-B in which A represents a single bond, an alkylenecarbonyl group or the like and B represents a substituted or unsubstituted piperidino group or the like, the other represents a tert-butoxycarbonyl group or the like, and Z represents a hydrogen atom or a triethylenesilyl group, and also to a drug containing the same. This compound has high solubility in water and also has excellent antitumor activities.
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申请公布号 |
CA2259977(C) |
申请公布日期 |
2005.06.28 |
申请号 |
CA19972259977 |
申请日期 |
1997.07.14 |
申请人 |
KABUSHIKI KAISHA YAKULT HONSHA |
发明人 |
NAGATA, HIROSHI;SAWADA, SEIGO;ABE, ATSUHIRO;YAEGASHI, TAKASHI;SHIMIZU, HIDEAKI |
分类号 |
C07D305/14;C07D405/12;C07D413/12;C07D413/14;(IPC1-7):C07D305/14;C07F7/10;C07D405/14;A61K31/335;A61K31/42;A61K31/445;A61K31/495;A61K31/535;A61K31/695 |
主分类号 |
C07D305/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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