| 发明名称 |
New spirotricyclic derivatives and their use as phosphodiesterase-7 inhibitors |
| 摘要 |
Spirotricyclic derivative compounds of formula (I) that are phosphodiesterase-7 (PDE7) inhibitors, and methods for preparing these compounds are disclosed, wherein A, X1, X2, X3, X4, X, Y, and Z are as defined in the specification. These compounds are suitable for the treatment of disorders for which therapy by a PDE7 inhibitor is relevant.
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| 申请公布号 |
NZ527847(A) |
申请公布日期 |
2005.06.24 |
| 申请号 |
NZ20020527847 |
申请日期 |
2002.03.18 |
| 申请人 |
WARNER-LAMBERT COMPANY LLC |
发明人 |
BERNARDELLI, PATRICK;DUCROT, PIERRE;LORTHIOIS, EDWIGE;VERGNE, FABRICE |
| 分类号 |
C07D239/78;A61K;A61K31/519;A61K31/527;A61K31/5365;A61K31/537;A61K31/5377;A61K31/5386;A61K31/542;A61K31/547;A61P;A61P1/00;A61P11/00;A61P11/06;A61P19/00;A61P19/02;A61P19/10;A61P25/00;A61P29/00;A61P31/12;A61P31/18;A61P35/00;A61P35/04;A61P37/00;A61P37/04;A61P37/08;C07D;C07D239/70;C07D239/80;C07D239/84;C07D401/04;C07D401/12;C07D403/04;C07D403/12;C07D405/12;C07D413/12;C07D487/10;C07D487/12;C07D487/14;C07D498/10;(IPC1-7):C07D239/70 |
主分类号 |
C07D239/78 |
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